Biological response modifiers are the newest class of drugs used to treat rheumatoid arthritis ra these modern biologics have greatly improved treatment for many people with ra. Aggressive treatment can help prevent long term disability from rheumatoid arthritis so if you have moderate to severe ra and dont respond to traditional disease modifying antirheumatic drugs . Biologic drugs are the newest type of treatment for rheumatoid arthritis ra and not only can they make a big difference in the way you feel but they can also help limit joint damage. Guideline for the treatment of rheumatoid arthritis american college of rheumatology acr last published a guideline for ra management in 2012 5 which was an update of the 2008 ra guideline 6 as biologics and tofacitinib including tapering and discon. In the late 1990s the first biologic drug went on the market to treat rheumatoid arthritis enbrel etanercept was first but it did not take long for other biologic drugs to be developed and marketed
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