The granulomatous disorders are a group of conditions affecting a wide range of organ systems in the body they are most commonly caused by infection and are characterized by multiple chronic inflammatory lesions this is a field that has opened up substantially in recent years because of the explosion in new molecular biology techniques. Chronic granulomatous disease cgd is an inherited genetic immune system disorder that occurs when a type of white blood cell phagocyte that usually helps your body fight infections doesnt work properly. Chronic granulomatous disease cgd also known as bridges good syndrome chronic granulomatous disorder and quie syndrome is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds . Chronic granulomatous disease cgd is an inherited disorder in which certain immune system cells do not function properly this leads to repeated and severe infection causes in cgd immune system cells called phagocytes are unable to kill some types of bacteria and fungi. Chronic granulomatous disease is a genetic disorder and is caused by inherited defects in an important enzyme in white blood cells that manufactures oxidants for microbial killing signs symptoms chronic granulomatous disease is characterized by a susceptibility to repeated bacterial and fungal infections
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